释义 |
VHLCOCA¹³⁹³⁸⁰ 基本例句 希佩尔-林道病¹⁰⁰ ResultsThe positive rate of VHL was significantly lower in lung cancer56.3% than that in normal lung tissues90.0% P0.01. 结果:肺癌组织 VHL表达阳性率56.3%明显低于正常肺组织90.0% P<0.01; xysm The main gene involved, the tumour suppressor VHL, is mutated in eight out of10 patients, but is not the whole picture. 主要涉及的基因是肿瘤抑制基因 VHL,十有八九的病人的 VHL会产生变异,但并不是全部。 yeeyan The VHL gene may be useful as a marker gene for the diagnosis of RCC and as a target gene for molecular therapy. VHL基因可作为临床诊断指标,并可望成为肾透明细胞癌基因治疗的重要目的基因。 cnki CNS hemangioblastoma is one of the most common manifestations of VHL disease. 中枢神经系统血管母细胞瘤是 VHL病最常见的表现。 dxyer Conclusion Biallelic inactivation of VHL gene occurs in RCC due to VHL mutation and LOH, and its frequency rate is37%. 结论肾细胞癌中存在由 VHL基因突变和 LOH导致的 VHL双等位基因失活现象, VHL双等位基因失活发生率为37%。 cnki Conclusion The VHL gene may frequently mutate in Chinese patients with primary sporadic renal clear cell carcinoma. 结论国人原发性散发性肾透明细胞癌中存在VHL基因的突变。 cnki Conclusion VHL gene abnormalities may play a critical role in renal cell tumorigenesis, It could be used as a predictor of early diagnosis of cRCC and for gene therapy to cRCC. 结论 VHL基因的检测可作为肾透明细胞癌的诊断指标, VHL基困可望成为肾透明细胞癌基因治疗的重要目的基因。 cnki Methods: The hypermethylation was examined by methyl sensitive restrictive DNA endoenzyme analysis in 34 cases of angioreticuloma and the VHL gene mutations detected by PCR SSCP analysis. 方法:采用 PCR SSCP法检测血管网织细胞瘤中 VHL基因的突变率及甲基化,敏感限制性内切酶消化法检测血管网织细胞瘤中 VHL基因的异常甲基化率。 cnki Methods The clinical and pathological data from6 patients with renal lesions in a large Chinese VHL disease kindred were reviewed individually. 方法回顾性分析6例同一VHL病家族伴有肾脏损害患者的临床及病理资料; cnki Most patients with isolated hemangioblastomas of the cerebellum do not have VHL. 大多数孤立性血管母细胞瘤并没有 VHL疾病。 china-radiology Mutation of VHL gene from tumor tissue was detected from tumor tissue by polymerase chain reaction PCR and direct sequencing. 采用单链聚合酶链反应 PCR和测序法检测肿瘤组织中 VHL基因的突变情况。 cnki Objective To evaluate the imaging manifestation of von Hippel Lindau VHL disease. 目的评价冯·希佩尔·林道病的影像学表现。 cnki Our aim was to look for overexpression of these molecules to identify precursor endocrine lesions in the pancreas of VHL patients. 本研究的目地就是通过寻找这些分子的过度表达,从而确认出 VHL患者在胰腺的前驱内分泌性病变。 pathology Results VHL gene mutation was detected in1035.7% CCRCC tumor samples. There was no mutation detected in all normal kidney tissues. 结果远离肿瘤的正常肾组织中未检测到 VHL基因的突变,10例35·7%癌组织标本中存在 VHL基因的突变。 cnki |