释义 |
prions 英p'riənz美p'riənz COCA⁶⁹⁰⁹⁴BNC¹⁴⁴⁶⁶⁴⁺³ 基本英英例句 proteinaceous infectious particles believed by some to cause Alzheimer's disease 蛋白质易传染粒子原型prion的复数 名词 prion: microbiology an infectious protein particle similar to a virus but lacking nucleic acid; thought to be the agent responsible for scrapie and other degenerative diseases of the nervous system“ Because there is no myelin damage at birth, we assumed prions are needed to maintain the quality of the myelin sheath, which diminishes throughout life, ” says Aguzzi. 因为老鼠在出生时没有髓磷脂损害,我们假设这种蛋白是为了维持髓磷脂的质量,并且在整个生命周期内会逐渐减小。 yeeyan “ So it is going to be interesting to see if prions play any role in demyelinating diseases that stem from the brain, ” he says. “如果小蛋白在脑部的其他疾病中都有影响那就更有趣了”,他说。 yeeyan Although these tests show that prions can force the waste disposal system to malfunction, they did not identify which part of the process went wrong. 尽管这些实验证明了朊病毒可以使废物处理系统故障,但它们并没有分辨出究竟是哪个环节出了错。 ecocn.org But it is not entirely clear what happens when the gene for normal prions is completely removed. 但是正常的朊病基因被完全敲除后到底发生了什么并没有完全搞清楚。 dxy By carefully measuring the rate at which proteasomes laboured, she found a clear correlation: as the clumps of prions in the sample got bigger, the proteasomes slowed down. 通过测试这些水解酶的工作速率,她发现了一个清晰的关系:当标本中的朊病毒团变大时水解酶的工作便慢了下来。 ecocn First Dr Tabrizi infected the nerve cells with disease-causing prions. 首先, Tabrizi博士向神经细胞注射了致病朊病毒。 ecocn.org I read recently that “ prions”, which are a type of protein, are been considered as conductors. 最近,我看了“朊病毒”,这是一种蛋白质,是被视为导体。 ordinaryslut In fact, at first glance, lack of prions seemed like a good thing because it made mice immune to prion infection. 事实上,在初期,缺少这种蛋白看起来和正常情况一样,因为它使老鼠免疫这种蛋白的缺失。 yeeyan In terms of the efficacy of disinfection, moist heat and various disinfection methods are not considered to be effective against prions. 按照灭菌的效率,温湿加热法和其他各种灭菌方法都不能被认为可以有效的对抗阮病毒。 dxy In addition to the prions, we now have the Gulf Stream! 不光是普里朊,现在又来了湾流! planta In51 survivors and their descendants, they discovered a hitherto-unknown variant of PRNP, the gene which makes prions, the proteins that spread the disease. 他们在51位幸存者和他们的后代身上发现了一种目前为止无人发现的 PRNP变体。 PRNP是含有库鲁病传染源——朊病毒——一种蛋白质的源代码。 yeeyan Like Dr Tabrizi, Dr Greenwood infected several types of mouse nerve cells with prions. 像 Tabrizi博士一样 Greenwood博士将朊病毒感染了数种老鼠神经细胞。 ecocn Nerve cells containing the prions stop working. The sufferer endures memory loss, personality changes and spontaneous, jerky bodily movements. Eventually, the disease kills him. 含有朊病毒的神经细胞失去正常功能,罹患者出现记忆减退、人格改变和自发的躯体急速抽动等症状,最后患者死亡。 ecocn Of further debate is the handling of devices that are known to be or are at high risk of being contaminated with prions, as reviewed elsewhere. 更进一步的讨论就是如何处理已知的或者很可能污染阮病毒的仪器,就像在别处讨论的那样。 dxy One possible approach to fighting the diseases involves knocking out the presence of prions altogether, including both the normal and abnormal forms. 战胜这些疾病的一个可能的途径就是完全破坏普粒子的出现,包括正常和非正常的。 dxy Overall, prions may not be highly resistant to reprocessing methods, depending on the process used, and efficacy against prions does not imply that other micro- organisms have been inactivated. 总之,在反复处理的过程中,阮病毒可能不是如此的有耐受性,这取决于使用何种方法。而且阮病毒灭活后也不能说明其他微生物也被灭活。 dxy Previous research showed that prions bind readily to these types of surfaces and can initiate infection with remarkable efficiency. 此前研究显示朊蛋白可便捷地与这些表面类型结合并以不同寻常的效率启动感染过程。 soudoc Recently scientists have started to think that prions might also disrupt the rubbish- disposal system, and that such interference might explain how they destroy nerve cells in the brain. 最近科学家也开始怀疑干扰废物处理系统的元凶也是朊病毒,而且这样的干扰也可以解释他们如何摧毁大脑的神经细胞。 ecocn.org Sarah Tabrizi of University College London, and her colleagues, have also examined the question of how prions kill nerve cells, transforming the brain into a spongy organ riddled with holes. 伦敦大学学院教授 Sarah Tabrizi和她的同事也对朊病毒杀伤神经细胞从而把大脑变成布满小孔海绵体的问题进行了研究。 ecocn.org Ten years later, he isolated small protein bodies, which he called prions, and showed that these were the cause of CJD and of the similar bovine spongiform encephalopathy. 十年后,他分离出了一些极小的他称为朊病毒的蛋白质微粒,并指出这些病毒就是绵羊庠病 CJD和类似的牛绵状脑病的病因。 yeebang That infectious prions cause rubbish to accumulate in brain cells may not be the only way in which they cause damage. 而朊病毒引起脑细胞垃圾的堆积也许不是灾难被引起的唯一方式。 ecocn They believe that infectious prions might wake viruses that lie dormant in the DNA of an uninfected cell. 他们相信感染朊病毒可能唤醒健康细胞内其他病毒沉睡的 DNA。 ecocn This suggests, by a similar seeding mechanism to that described for prions, that such diseases could be transmissible under certain situations, including transfer uncontaminated surfaces. 这就暗示了,通过与阮病毒相似的传播机理,这种疾病可以在特定条件下传播,包括通过污染的表面传播。 dxy Prions are the infectious agents responsible for transmissible spongiform encephalopathiesTSEs, which are a group of fatal neurodegenerative diseases. 可传播性海绵状脑病是一类由朊病毒侵袭中枢神经系统而引起的致死性神经退行性疾病。 dictall Prions are simple proteins that are much smaller than viruses. They are unique since they lack a genome. All other known infectious agents contain genetic material. 朊蛋白是一个非常简单的蛋白,比病毒更为简单。它们非常特殊,因为它们没有基因组。所有其它已知的传染性因子都含有遗传物质。202.204.208.83 |