释义 |
pri·on 英ˈpriːɒn美ˈpriɑnAHDprēʹŏn 高COCA⁴⁶⁷³⁷BNC⁴⁴¹²²iWeb²⁸⁷⁶⁷ 基本英英词源例句例句 n.朊病毒感染性蛋白质
Noun: microbiology an infectious protein particle similar to a virus but lacking nucleic acid; thought to be the agent responsible for scrapie and other degenerative diseases of the nervous system一种小鸟。来自希腊语prion,锯子,来自prizein,锯,使成碎片,词源同prism.后用于指这种小鸟,因其鸟喙形如小锯子而得名。 名词100% 用作名词Until that question is answered, the new era of theprionwill remain confusing and frightening.如果这一问题得不到解答,朊病毒的新时期将仍然充满困惑和恐惧。 Still, scientists say new forms ofpriondiseases have arisen lately, and there's concern that they could hop to humans.尽管如此,科学家说近来出现了一些新的朊病毒疾病,人们担心这些疾病可能会传播到人类身上。 Complementary DNA cDNA sequence of Japanese sea bassLateolabrax japonicus prion proteinPrP encoding gene was cloned and characterized through RT- PCR approach. 采用 RT- PCR方法分离了鲈鱼蛋白质感染因子蛋白编码基因序列,并进行了结构分析。 iciba Simon Mead of the British prion research centre at University College London says the discovery of an “ anti- kuru” gene is the most clear-cut evidence yet of human evolution in action. 伦敦大学学院下属英国朊病毒研究中心的西蒙·米德表示,抗库鲁病基因的发现,是人类还在不断进化最有说服力的证据。 yeeyan But if an absence of healthy prion protein was severely detrimental, then we might have to rethink this therapeutic approach. 但是如果能证明 CJD确实是由小蛋白的缺失造成的,那么我们就会重新考虑治疗方法。 yeeyan But it's not yet known whether the variant protects against other prion diseases. 但是目前还不清楚这一变异是否对其他由朊病毒引起的疾病有效。 yeeyan But no variant of prion protein was able to prevent demyelination when introduced specifically into the Schwann cells that surround and support peripheral nerve cells. 但当向神经末梢周围的雪旺细胞注入这种蛋白时,没有变异的蛋白能阻止退化。 yeeyan Conclusion: Prion protein106-126 peptide has cellular toxicity effect on differentiated PC12 cells, and the energy metabolize disorder may be one of the reasons for the toxic mechanism. 结论:朊蛋白106-126肽段对分化 PC12细胞具有毒性作用,能量代谢障碍可能是其毒性作用机制之一。 cnki Could RNA interfere with prion disease? RNA能否干预普粒子疾病? dxy He also has a hunch, supported by preliminary data, that prion proteins will turn out to play the same part in supporting myelination in the brain. 他还有大量的支持他理论的基础数据,小蛋白在脑子的髓鞘的形成中起了相同的作用。 yeeyan However, other scientists are skeptical and believe that the prion protein is a viral coat protein that protects a small nucleic acid that has not yet been detected. 然而,另外的科学家表示怀疑,他们相信普利昂蛋白是病毒中用于保护至今还未被检测到小核酸的衣壳蛋白。 shxy.wzu.edu.cn However, prion diseases are considered to be representative of other protein precipitation- associated diseases. 然而,阮病毒疾病被认为是其他蛋白相关疾病的典型。 dxy In 2003, Mead and his colleagues discovered a much more common variant of the prion gene that provides protection against prion diseases. 2003年,米德和他的同事发现了朊病毒基因更普遍的变体,可以抗御与朊病毒有关的疾病。 yeeyan In fact, at first glance, lack of prions seemed like a good thing because it made mice immune to prion infection. 事实上,在初期,缺少这种蛋白看起来和正常情况一样,因为它使老鼠免疫这种蛋白的缺失。 yeeyan In this course, the molecular and biochemical basis of the prion diseases, which include bovine spongiform encephalopathymad cow disease, Creutzfedt-Jakob disease and kuru will be examined. 在本课程中,我们将分析包括了牛海绵体样脑病疯牛病,克雅氏症,以及库鲁病的朊蛋白疾病的分子和生化的成病基础。 myoops Removal of prion contamination is a complicated matter, with studies showing that cleaning chemistries can decrease or even increase the resistance of prion contamination to steam sterilization. 去除阮病毒的污染是个复杂的事情,研究表明用化学试剂清洗可以降低或者增加阮病毒对蒸汽灭菌的抑制。 dxy Surgeon or Designee will notify the Operating Room of the brain biopsy of suspected prion disease. 外科医生或操作者应通知可疑朊毒体病人进行脑组织活检的手术室。 bbs.icchina.org.cn Together with his colleagues, he studied four different strains of mice lacking the gene for the prion PrPC. 他和他的同事们研究了四种缺少这种蛋白基因的老鼠。 yeeyan When he added an anti- prion drug to the mix, though, the virus production halted. 而混合了抗朊病毒药物后,老病毒的生产就停止了。 ecocn Prion diseases are always fatal, often, however, not until months after the outbreak of the disease. As yet there is no cure. 朊病毒病是致命的,常常在发病后数月死亡,但是目前还没有有效的治疗方法。 med66 Prion diseases or transmissible spongiform encephalopathyTSE diseases are rare fatal neurodegenerative diseases of humans and other animal. 朊病毒疾病即海绵状脑病,是人和动物中的一类致死性中央神经系统疾病。 cnki |