释义 |
Ph chromosome 基本例句 费城染色体 Cytogenetically,Ph chromosomewas seen in 25.5% of patients with BAL.核型分析揭示BAL中Ph染色体较多见,占25.;5%; Objective:To investigate the value of detection ofPh chromosomeand bcr/abl fusion gene in the diagnosis of CML.目的 :观察Ph染色体 ,bcr/abl融合基因与慢性粒细胞白血病 的诊断指标。 Chronic myelogeous leukemia is a clonal disorder of a pluripotent hematopietic stem cell associated in over 95%of cases with thePh chromosome.慢性粒细胞白血病是骨髓多能造血干细胞恶性增殖性疾病。 Four in 485 CML cases were not detected with typicalPh chromosomeby G-banding, but with Ph-masked variant translocation by FISH.485例CML患者中4例经常规G显带技术未见典型Ph染色体;FISH检出具有隐匿型Ph染色体。 Method:Bcr/abl fusion gene andPh chromosomewere assayed by RT-nest-PCR and routine cytogenetic analysis, respectively.方法:分别采用RT-nest-PCR法和常规细胞遗传学方法检测bcr/abl融合基因和Ph染色体。 Methods:To detect mRNA levels of bcr-abl fusion gene of 36 patients with CML by RQ -PCR and nested RT-PCR ,Ph chromosomeusing cytogenetic study.方法:采用实时定量逆转录聚合酶链反应及巢式RT-PCR方法检测36例CML患者bcr-abl mRNA; 并用细胞遗传学方法检测Ph染色体。 |