释义 |
parp 英'pɑːrp美'pɑːrp BNC²³⁶²¹³⁺¹ 基本例句 n.喇叭声; 鸣响喇叭声 Objective: To observe the expression of poly ADP- ribose polymerase PARP in focal cerebral ischemia with reperfusion injury and explore the role of PARP in apoptosis. 目的观察多聚 ADP核糖聚合酶 PARP在脑缺血再灌流损伤中的表达,探讨 PARP在细胞凋亡中的作用。 cnki To estimate the relative risk and the population attributable risk percent PARP of main risk factors by comprehensive analysis. 利用综合分析方法估计我国人群三种肿瘤的主要危险因素的相对危险度及人群归因危险度百分比。 cnki “ In blocking PARP-1, you block DNA repair, ” he cautions. “在抑制 PARP-1的同时,也阻止了 DNA修复。”他提醒道。 gd But a new category of drug called PARP inhibitors may change that. 然而一种名叫 PARP抑制剂的药物可能会改变现状。 yeeyan Cancer cells with the BRCA1 or BRCA2 mutations are the first to be shown to be sensitive to PARP inhibitors. 带有 BRCA1或 BRCA2突变的癌细胞是第一个显示出对 PARP抑制剂敏感的细胞。 suiniyi Depending on the nature and extent of the damage, PARP-1 can trigger either DNA repair, an inflammatory response, or apoptosis? so-called cell suicide. 根据损伤的类型和程度, PARP-1能触发 DNA修复,免疫反应或者凋亡也即细胞自杀。 bioon In the study, conducted in cell culture, the team determined that the drug blocks the action of poly ADP-ribose polymerase-1 PARP-1, a protein that can trigger inflammation and cell death. 在细胞培养试验中,研究小组已认识到该药物能阻断糖化 ADP多聚酶-1 PARP-1的活性,而该蛋白质会激发机体的免疫反应和细胞凋亡。 gd Objective To investigate the expression of Poly ADP- Ribose Polymerase PARP and morphological changes after varies duration of retinal ischemia reperfusion in rats. 目的观察大鼠视网膜缺血再灌注损伤后不同时相视网膜结构变化及多聚二磷酸腺苷核糖聚合酶 PARP的表达情况。 iciba Objective To investigate nucleotide polymorphisms of five exons in human polyADP- ribosepolymerase-1 PARP-1 gene. 目的检测人类聚腺苷二磷酸核糖聚合酶-1 PARP-15个外显子核苷酸多态性。 chemyq The first is that PARP-1, a protein found in every cell, becomes activated whenever a cell's DNA is damaged. 第一是观察到 PARP-1存在于每个细胞中,并且当细胞 DNA受损伤时能激活该蛋白质。 bioon The study authors conclude that it is very likely that minocycline's neuroprotective and anti- inflammatory effects are due to PARP-1 inhibition. 文章的作者总结道,二甲胺四环素的神经保护和抗炎作用很可能是由于抑制了 PARP-1。 gd When DNA damages of cells appear, as a kind of molecular sensor of cells, PARP will recognize and bind to DNA breakages, then be activated. 当细胞 DNA发生损伤时, PARP可作为细胞内的分子感受器,识别、结合到 DNA断裂处,并被激活。 cnki PARP inhibition may prove beneficial for the treatment of atherosclerosis. PARP抑制可能会被证实对动脉粥样硬化的治疗有帮助。 med66 |