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词汇 oligonucleotides
释义 oligonucleotides 英ɒlɪɡən'juːkliːəʊtaɪdz美ɒlɪɡən'juːkliːəʊtaɪdz COCA¹³⁶³⁵⁶BNC²⁵¹⁹²
基本例句
寡核苷酸¹⁰⁰原型oligonucleotide的三单 A method of polyamide thin layer chromatography applicable to the separation and identification of blocked nucleosides, nucleotides and oligonucleotides is herewith described.
本文介绍了用聚酰胺薄层层析的方法,分离和检定带保护基的核苷、核苷酸和低聚核苷酸。 cnki

Among them, a newly developing technology, called targeted gene repair mediated by oligonucleotides, is a better way for genetic disorders than traditional strategies.
近年来新兴的寡核苷酸介导的基因定点修复技术,就是其中一种比传统策略更具优越性的基因治疗方法。 cnki

No obvious difference was found in the sense and no- sense oligonucleotides groups and blank control group P>0.05.
正义寡核苷酸治疗组、无义寡核苷酸治疗组和空白对照组之间差异不显著 P>0.05。 cnki

The application of polymer supports for the synthesis of polypeptides, oligonucleotides, and oligosaccharides is presented in this article and discussed in view of their methodology.
应用聚合物支持合成多肽,寡核苷酸,并低聚糖是本文中介绍和讨论,鉴于它们的方法。 syyxw.com

To quantify the products of single nucleotide primer extensionSNuPE, the single strain oligonucleotides were separated by High Performance Liquid Chromatography HPLC.
建立用普通高效液相色谱仪检测单链寡聚核苷酸的方法,为检测单碱基引物延伸反应的产物提供定量分析基础。 cnki

AimTo synthesize ribonucleoside-incorporated oligonucleotides and investigate their binding abilities with complementary sequences.
目的合成异核苷掺入寡核苷酸并考察它们与互补序列的结合能力。 dictall

Antisense strategy is a kind of newly rising biotechnology which can selectively block gene expression by using sequence-specific antisense oligonucleotides.
反义技术是应用反义寡核苷酸来选择性地封闭基因表达的一项新兴的生物技术。 cnki

Antisense oligonucleotides can specifically inhibit or drowregulate homologous gene expression, so it might be a good choice of genetic therapy.
反义寡核苷酸可特异性抑制或下调同源基因表达,从而能成为基因治疗的首选药物。 cnki

Antisense oligonucleotides have been successfully employed to inhibit and modulate specifically gene expression.
反义寡聚核苷酸已成功用于对基因表达的特异性调控与抑制。 chemyq

As compared to conventional drugs that work on proteins, antisense oligonucleotides work on RNA.
与传统的作用于蛋白质的药物相比,反义寡聚核苷酸作用于 RNA。 dxy

Disclosed are oligonucleotides for manipulating an immune reaction.
本发明公开了用于操纵免疫反应的寡核苷酸。 www.patenta4.com

During oligonucleotide immobilization, terminal amino modification has no obvious specificity, but it can enhance the hybridization capacity of immobilized oligonucleotides.
寡核苷酸固定过程中,末端氨基修饰没有明显的特异性,但是可以提高被固定探针的杂交容量。 cnki

However, unlike most of the DNA and RNA oligonucleotides, PNAs are poorly penetrated through the cell membrane, partially due to their uncharged property.
然而,与大多数 DNA和 RNA寡核苷酸不同,肽核酸的透膜能力很差,部分原因是由于它们具有不带电荷的性质。 blog.sina.com.cn

Important new applications that could not be performed using natural oligonucleotides have emerged.
许多重要的、用天然寡核苷酸无法实现的新应用也应运而生。 blog.sina.com.cn

Objective To investigate the effect of IL12 antisense oligonucleotides on immunoglobulin secretion by PBMC from patients with active lupus nephritis LN.
目的探讨 IL12反义寡核苷酸对狼疮肾炎 LN患者单个核细胞PBMC分泌免疫球蛋白的影响。 cnki

Objective To study inhibition of VEGF expression in human bladder carcinoma cells by antisense oligonucleotides.
目的观察 VEGF反义寡核苷酸对膀胱癌细胞 VEGF表达的抑制情况。 chemyq

Objective: To investigate the growth inhibition of antisense oligonucleotides of telomerase on liver tumor cell enhanced by albumin nanoparticles.
目的:利用纳米载体增强端粒酶反义寡核苷酸对肝脏肿瘤细胞生长的抑制作用。 cnki

Results VEGF antisense oligonucleotides obviously inhibited VEGF expression in human bladder carcinoma cells and proliferation of endothelial cells.
结果 VEGF反义寡核苷酸对膀胱癌细胞的 VEGF表达有明显的抑制作用。 chemyq

Suppose you are working with oligonucleotides32 nucleotides in length.
假设你在用32核苷酸长度的寡核苷酸工作。 tdict

The invention relates to compositions active for oligonucleotides delivery into eukaryotic cells in culture, ex vivo or in vivo.
本发明涉及能够在培养物中、离体或者体内将寡核苷酸输送入真核细胞的组合物。 www.patenta4.com

The paper provide a new strategy for clinical prevention and treatment with vascular intimal hyperplasia by photodynamic therapy with antisense oligonucleotides modified by photosensitizer.
本文拟通过光敏剂修饰反义寡核茬酸介导光动力疗法防治内膜增生,以期为临床防治术后血管再铗窄提供新的手段。 cnki

The present invention relates to regulate activity of target RNA oligonucleotides.
本发明涉及用于调节靶 RNA活性的寡核苷酸。 www.patenta4.com

The porphyrin moiety was modified on the commercial oligonucleotides through the active1- hydroxybenzotriazole esters of the porphyrins.
利用卟啉的1-羟基苯并三氮唑活性酯可将卟啉基团直接修饰在商品化的寡核苷酸片断上。 cnki

Ultraviolet crosslinking greatly affected the attachment rate of a large fragment of DNA, but did not noticeably affect the attachment rate of the amino- modified oligonucleotides.
紫外交联对大片段 DNA固定率影响显著,但对氨基修饰的寡核苷酸影响不显著; cnki

We have developed a program SOAP for efficient gapped and untapped alignment of short oligonucleotides onto reference sequences.
我们开发了一个程序 SOAP以高效地带有间隔或不带间隔地将短寡核苷酸比对到参考基因组上。 chinapubmed.net
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