释义 |
NONMEM 基本例句 非线性混合效应模型¹⁰⁰ Here we introduced the clinical application development ofNONMEMand analyzed recent ten years of typical internal and external documents.本文通过对国内外近十年来大量运用该法研究的论文进行归纳整理,介绍群体药代动力学研究中非线性混合效应模型法的临床应用进展。 Nonlinear mixed effect model has been widely used in estimating population pharmacokinetics parameters of various drugs.非线性混合效应模型法广泛应用于临床各类药物的群体药动学参数估算。 Nonlinear mixed effect model非线性混合效应模型法 Keywords Nonlinear mixed effect modelNONMEM;Clinical application;Development;非线性混合效应模型法;临床应用;进展; Keywords cyclosporine A;renal transplantation;population pharmacokinetics;NONMEM;Michaelis-Menten model;环孢素A;肾移植;群体药动学;NONMEM;米-曼氏模型; Keywords epilepsy;children;population pharmacokinetics;population pharmacodynamics;valproate;NONMEMsoftware;癫痫;儿童;丙戊酸钠;群体药动学;群体药效学;NONMEM法; |