| 释义 |
mll 英'em'el'el美'em'el'el COCA²¹⁴³²⁸BNC²³⁶²¹³⁺¹
基本例句
=malignant lymphoma,lymphoblastic 恶性成淋巴细胞性淋巴瘤,=mixed lymphocytic lymphoma 混合淋巴细胞性淋巴瘤
Conclusions Genotypes defined by the mutational status of NPM1, FLT3, CEBPA, and MLL are associated with the outcome of treatment for patients with cytogenetically normal AML.
结论：由 NPM1， FLT3， CEBPA，和 MLL基因的突变状态所界定的基因型与细胞遗传学正常的急性髓细胞白血病患者的临床治疗结局之间存在相关性。 dxy
The investigators created a mouse model to track the function of a gene called MLL, which stands for Mixed Lineage Leukemia.
一旦这些基因无法正常工作，白血病就发生了。 bbioo
The one of most interesting issues is how leukemia cells with MLL rearrangement acquire a unique feature of TRAIL- resistance.
非常有意思的问题之一是有 MLL重排的白血病细胞怎样获得抵抗 TRAIL的唯一特征。 dxy
MLL fusion genes likely co-opt normal MLL functions in blood cells, leading to the overproduction of white cells and leukemia.
融合后的基因含有正常 MLL功能，这会导致白细胞过度增生，最终形成白血病。 ewsos
After sequential R- banding and FISH analysis for6 patients, the chromosome related to MLL gene translocation was seen clearly in karyotypes and FISH image.
对6例患者进行连续 R显带后 FISH分析后，对照核型和 FISH图都能清楚地看到 MLL基因易位涉及的染色体。 cnki
Gene expression profile analysis of the ALL cells demonstrated significant overlap with human MLL-rearranged ALL.
ALL细胞基因表达状况分析表明其与人 MLL重排的 ALL具有相当的重叠。 ggene.cn
Here, we present a crystal structure of WDR5 bound to an MLL peptide.
此研究中，研究者解析了 WDR5与 MLL多肽结合的晶体结构。 ggene.cn
However, the team also found high levels of another protein called Hoxa9 in the MLL mice and human patients.
不过，研究小组也在 MLL小鼠与人类患者体内发现高水平的 Hoxa9蛋白。 stemcell8
In this case, the duplication within the MLL gene contributes to an aggressive form of AML.
这种情况下， MLL基因中的复制导致 AML的的侵略性。 dxy
In normal cells, MLL combines with four proteins that comprise the W- RAD group to create a molecular switch that controls DNA packaging events required to form white blood cells.
在正常细胞中， MLL与其他四种蛋白联合组成了 W- RAD复合体，从而形成了在白细胞形成中所需的一种控制 DNA组合的分子开关。 dxy
Inhibition of GSK3 in a preclinical murine model of MLL leukaemia provides promising evidence of efficacy and earmarks GSK3 as a candidate cancer drug target.
在 MLL白血病一个临床前鼠模型中，抑制 GSK3可提供有效性的令人鼓舞的证据，并标记了 GSK3作为候选的癌症药物靶点。 papssl
The genetic change, known as a partial tandem duplication, is located in a gene called MLLfor mixed-lineage leukemia.
该基因改变，即所谓的部分串联复制，位于 MLL混合血系白血病基因上。 dxy
Thus, further exploration is necessary to overcome the TRAIL- resistance of ALL with MLL rearrangement.
因此需要进一步研究才能克服说明所有带有 MLL重排的细胞都抵抗 TRAIL。 dxy
We suggest that the activity of the MLL complex might be regulated through this interplay.
研究者认为， MLL复合物的活性可能受到这些相互作用的调控。 ggene.cn
We thus demonstrate that ectopic H3K79 methylation is a distinguishing feature of murine and human MLL- AF4 ALLs and is important for maintenance of MLL- AF4- driven gene expression.
因此，研究者认为异位的 H3K79甲基化是区分小鼠和人 MLL- AF4的重要依据，并且对驱动 MLL- AF4基因的表达有重要作用。 ggene.cn
When the MLL switch is broken, white blood cells do not mature properly, resulting in a dangerous proliferation of abnormal cells.
当 MLL开关被破坏后，白细胞就无法正常成熟，并导致一种危险地非正常细胞的增殖。 dxy |