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词汇 hypomethylation
释义 hypomethylation 英haɪpɒmiːθɪ'leɪʃən美haɪpɒmiːθɪ'leɪʃən BNC²³⁶²¹³⁺¹
基本例句
低甲基化¹⁰⁰
Both global hypomethylation and hypermethylation“ coexist in all tumors and can contribute to tumor development and progression through different mechanisms, ” he said.
广泛低甲基化和高甲基化“共存于所有肿瘤且以不同的机制导致肿瘤的发展和恶化,”他说。 dxy

DNA hypomethylation often displays considerable specificity with regard to tumor type, tumor stage, and sequences affected.
DNA甲基化且与肿瘤类型、肿瘤分期及肿瘤侵袭的顺序中表现出相当的特异性。 chemyq

DNA hypomethylation, likely to be cooperating with aberrant histone modification, may induce the activation of some T cell genes and development of autoimmunity in SLE.
DNA的低甲基化可能在异常组蛋白修饰的协同下引起某些 T细胞基因的异常活化,导致狼疮自身免疫的发生。 cnki

DNA hypomethylation was the initial epigenetic abnormality recognized in human tumors.
DNA低甲基化是在人类肿瘤中识别的最初的表观遗传异常。 chinapubmed.net

Global hypomethylation and regional hypermethylation are common mechanisms of aberrant expression of gene.
广泛的低甲基化和区域性高甲基化是基因异常表达的常见机制。 kns50.chkd.cnki.net

In this review, active demethylation of DNA and the relationship of cancer- associated DNA hypomethylation to cancer stem cells are discussed.
在这篇综述中,讨论了有效的 DNA去甲基化及癌症相关 DNA低甲基化和癌症干细胞间的关系。 chinapubmed.net

Objective: To examine the extent of total genomic DNA methylation in hepatocellular carcinoma and the relationship between the DNA hypomethylation. and histopathologic characteristics.
目的:研究原发性肝细胞癌组织中总基因组 DNA甲基化水平及其与病理学及生物学行为的关系。 cnki
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