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单词 hirudin
释义 hir·u·din 英hɪəˈruːdn, ˈhɪərədən, -jə-美hɪrˈrudņ, ˈhɪrədən, -jə-AHDhîr-›dʹn, hîrʹə-dən, -yə- BNC⁹⁷²³³⁺
基本例句
n.生化水蛭素
A positive correlation was found between the concentration of crude hirudin and the inhibition of platelet aggregation;
水蛭粗提取液的浓度与人血小板聚集的抑制率呈正相关系; cnki

Administration of hirudin reduced both brain water content and BBB permeability.
水蛭素能够降低各个时间点的脑水含量和 BBB通透性。 cnki

And the fibrinogen method in vitro and a canine blood coagulation model were used to identify how batroxobin antagonize the bleeding effect of hirudin.
采用体外纤维蛋白原法、体内狗动物模型研究巴曲停拮抗水蛭素的抗凝血作用。 fabiao

However, the drug may be released quickly and completely from coated-pellets in the simulated intestinal fluid, which contributed to absorption of recombinant hirudin.
在人工肠液中药物释放快速而且完全,有利于水蛭素在肠道中的吸收。 cnki

In addition, the bleeding liability induced by the recombinant fusion protein was less than that of hirudin.
等摩尔浓度下,融合蛋白的出血倾向也明显小于水蛙素。 fabiao

PurposeThe aim is to obtain recombinant hirudin gene using PCR method.
目的应用 PCR方法获得水蛭素基因。 cnki

The recombinant fusion protein didn't affect the blood coagulation indices, but hirudin and heparin did obviously in the normal rabbits when administered alone at the same dose.
并且等剂量条件下,融合蛋白不硕士论文影响正常兔凝血指标的改变,而水蛙素和肝素则明显改变兔凝血指标; fabiao

The successful display of hirudin on the surface of M13 phage laid a sound foundation for the further study on directed evolution of antithrombotic proteins with altered properties.
水蛭素在噬菌体表面的功成展示为进一步开展其实验定向进化以及结构与功能关系的研究打下基础。 cnki

The anticoagulation effect of hirudin was better than dipyridamole P0.01.
水蛭素抗凝作用明显强于潘生丁 P0.01。21mishu

The treatment group was treated with r- hirudin;
治疗组应用重组水蛭素; taofanwen

CONCLUSION The transport of recombinant hirudin across xenopus pulmonary membrane was a passive diffusion process which was energy- independent and carrier- independent.
结论重组水蛭素经蟾蜍肺泡膜的转运是一个非能量依赖、非载体依赖的被动扩散过程。 cnki

Conclusion Damage to the thalamic tissue might be caused by thrombin and reversed by hirudin.
结论凝血酶对丘脑组织具有毒性损伤作用,但这一损伤可被水蛭素逆转。 cnki

Conclusion Thrombin can lead to brain edema after cerebral hemorrhage which can be restrained by Hirudin. And then, hirudin doesn't produce any negative effect on brain tissue.
结论凝血酶可以引起脑出血后脑组织水肿,水蛭素可以抑制凝血酶所引起的脑水肿且水蛭素本身不对脑组织产生负面影响。 cnki

ConclusionThe experiments show that hirudin active factors have strong inhibition effect on Sh0 Tumor and CAM angiogenesis.
结论实验表明,水蛭素活性因子对 Sh0肿瘤和 CAM新生血管具有较强的抑制作用。 yxyjzz

However, low production of natural hirudin, which was very expensive, limiting its use of in clinical practice.
但是天然水蛭素产量低,价格昂贵,限制了它在临床上的运用。 yywkt

Objective To evaluate the effect of locally applied hirudin on the expanded flap venous congestion.
目的探讨局部应用水蛭素对扩张皮瓣静脉淤血的防治作用。 cnki

Objective To investigate the effect of hirudin injection on the brain blood flow of dog and brain edema of cerebral infection in mice.
目的观察水蛭肽注射液对犬脑血流量及大鼠缺血性脑水肿的影响。 cnki

Objective To observe the effect of acute ischemic stroke treated with hirudin.
目的观察重组水蛭素治疗急性缺血性脑卒中的疗效。 taofanwen

Objective: To investigate the anti- tumor mechanism of hirudin.
目的:探讨复方水蛭素抗肿瘤的作用机理。 yxbwk.njournal.sdu.edu.cn

OBJECTIVE Progress in different routes of administration and formulations for Hirudin are reviewed.
目的阐述水蛭素不同给药途径及相关剂型的研究进展。 kns50.chkd.cnki.net

ObjectiveTo explore the effect of hirudin active factor on Sh0 tumor and angiogenesis so as to provide the theoretical basis for clinical medication.
目的探讨水蛭素活性因子对 Sh0肿瘤及血管新生的影响,为临床用药提供理论依据。 yxyjzz

Results The drug content of prepared recombinant hirudin coated-pellets was3.513%w.
结果所制备的重组水蛭素肠溶包衣微丸药物含量质量分数为3.513%。 cnki

ResultsA large quantity of hirudin gene was established.
结果获得水蛭素基因。 cnki

The pharmacological action, dose, security and stability of hirudin are summarized, and its availability is analyzed to provide some references for the relevant research.
从水蛭素药理作用、剂量及安全性、稳定性方面,对水蛭素的可利用性进行了分析,旨在为相关研究奠定基础。 kns50.chkd.cnki.net

Hirudin has good pharmacological action, which is widely used in clinical practice.
水蛭素具有较好的药理作用,其药源丰富,在临床上应用广泛。 kns50.chkd.cnki.net

Hirudin is an anticoagulant directly acting on thrombin. Its molecular biological and pharmacological properties, mechanism of action, current clinical researches and uses were reviewed.
水蛭素是特异的直接作用于凝血酶的抗凝剂。本文概述了其分子生物学特性、药理学特征、作用机理以及临床应用状况。 cnki
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