| 释义 |
Fmoc
基本例句
9-芴甲氧羰基可用作氨基保护基
Single protected amino acids used base-labileFmocto protect amido, such asFmoc-Gly-OH,Fmoc-L-Leu-OH,Fmoc-L-Ile-OH andFmoc-D-Val-OH.单保护氨基酸主要采用碱敏感的芴甲氧羰酰基来保护,主要的品种有:Fmoc-Gly-OH、Fmoc-L-Leu-OH、Fmoc-L-Ile-OH和Fmoc-D-Val-OH。
Two biotin containing lysine derivatives, Boc Lys OH andFmocLys OH were synthesized starting from lysine.以赖氨酸为原料 ,合成了两种含生物素的赖氨酸衍生物 Boc-Lys -OH和Fmoc-Lys -OH。
DMF is used as the coupling solvent; Piperidine-DMF to removed theFmocgroup; TBTU/HOBt/DIEA as the activation system,and TFA/EDT/TIS/H_2O as the cleavage condition.以DMF为反应溶剂;Piperidine-DMF脱去Fmoc保护基团;以TBTU/HOBt/DIEA作为肽键缩合试剂进行接肽反应;用TFA/EDT/TIS/H2O定量地从树脂上切除;制备型高效液相色谱分离纯化粗肽.
Three insulin A-chain analogues with substitution by basic amino acia residues at A8-10 positions inside the intra-disulfide bonds were synthesized by the solid phase methods withFmocprotection strategy.本文报道了用Fmoc固相法合成3种胰岛素A链小环A8－10被不同碱性氨基酸取代的A链类似物，并分别与天然胰岛素B链重组成相应胰岛素类似物；
solidphase synthesis; peptides; MSH;Fmoc固相合成；肽类；MSH；芴甲氧羰基
Keywords solid-phase synthesis;peptides;MSH;Fmoc;固相合成;肽类;MSH;芴甲氧羰基; |