释义 |
alk. 基本例句 abbr.=alkali In this study, it appears that ALK gene mutations also trigger the production of neuroblastoma cells. 这项研究显示, ALK基因突变同样引起神经母细胞癌细胞的增殖。 dxy The expressed ALK was in the cytoplasm and the nucleus. ALK蛋白表达模式为细胞质与细胞核。 cnki This fusion results in increased activity of ALK, which was already known to be implicated in a certain type of lymphoma. 融合导致了 ALK的激增活动,之前已经发现可以导致某种淋巴癌。51qiji In 2007 a group of researchers discovered that the fusion of two normally independent genes, EML4 and ALK, into one aberrant gene seems to drive the formation of tumours. 2007年一个研究小组发现,两种普通基因 EML4和 ALK和一个异常化基因的融合能形成肿瘤。 ecocn Objective To study the clinicopathologic features of diffuse large B- cell lymphoma DLBCLwith expression of anaplastic lymphoma kinase ALK protein. 目的探讨表达间变性淋巴瘤激酶 ALK蛋白的弥漫性大 B细胞淋巴瘤 DLBCL的临床病理特点。 cnki Preferably, investigative immunohistochemistry of this case should include two T cell markers, two B cell markers, CD30, EMA and ALK-1. 此例较合适的研究性免疫组化项目包括两个 T细胞标记物,两个 B细胞标记物, CD30, EMA,和 ALK-1。 www.ipathology.net.cn Purpose To explore the significance of diffuse large B- cell lymphoma DLBCL with a granular cytoplasmic staining for anaplastic lymphoma kinase ALK and their morphologic variants. 目的探讨间变性淋巴瘤激酶 ALK阳性的弥漫性大 B细胞淋巴瘤的组织病理形态和免疫组化表达的意义。 cnki Scientists already knew that abnormalities in ALK were linked to lymphoma and lung cancer, where it triggers the translocation of DNA between chromosomes to make new cancer-causing genes. 科学家已经知道 ALK的异常和淋巴瘤还有肺癌的的发病有关。 ALK的异常引起染色体之间 DNA的置换,从而引起新的癌症基因的突变。 dxy Several drug companies are already developing ALK inhibitors, and one is going through early phase adult clinical trials for treating lung cancer and lymphoma. 一些药品公司已经正在研制 ALK抑制剂,而且一个公司已经正在进行对肺癌和淋巴瘤的成人早期临床试验。 dxy She explains that alk phosphatase vaguely suggesting that there is something wrong with your liver or your bones. 她当时只是含糊地解释说这个指数说明你的肝脏或者骨骼可能有问题。 yeeyan The second part of this dissertation is on the synthesis of the key intermediate of ALK, a new Antihypertensive agent. 本论文第二部分的内容是抗高血压新药ALK重要中间体的合成研究。 cnki The researchers sequenced both genes and found mutations in ALK. 研究人员将这两个基因分别测序,在 ALK上发现了变异。 dxy There are other examples of success in specifically targeting genetic changes in never- smokers with lung cancer, such as treatments of tumors with alterations in the EML4- ALK gene. 针对不吸烟者的基因改变进行靶向治疗,这有些其它的成功例子,比如针对有 EML4- ALK基因改变的肿瘤进行的治疗。 yeeyan They found mutations in the ALK gene that cause it to be constantly active in helping cells proliferate. Out- of- control proliferation is the hallmark of cancer. 他们发现引起神经母细胞瘤的 ALK基因突变一直很活跃这助长了细胞的增生。细胞增生失去控制是癌症发生的标志。 dxyer This abnormality is an obvious target for treatments that inhibit the ALK protein that delivers the trigger. 这种异常机制是对抑制传递这种激活的 ALK蛋白质的疗法是一个明显的靶标。 dxy Translocations can affect the ALK gene resulting in the expression of oncogenic fusion proteins. 易位可以影响 ALK基因在致癌融合蛋白的表达。 oneyao |